Source: | Rabbit | Gene Id: | 6605 |
Isotype: | IgG | Swiss Prot: | Q969G3 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF IP CHIP |
Clonality | Polyclonal Antibody |
Calculated MW | 46kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
ChIP 1:20 - 1:100
|
Immunogen | A recombinant protein of human SMARCE1 |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | BAF57 |
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