RAD17 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5884-01 50ul 1500.00 In Stock
ARP5884-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5884
Isotype: IgG Swiss Prot: O75943
purity: Affinity purification
Background:
The human checkpoint protein Rad17 and its fission and budding yeast orthologues (Schizosaccharomyces pombe Rad17 and Saccharomyces cerevisiae Rad24, respectively) are involved in the activation of checkpoint signals in response to DNA damage or disruption of DNA synthesis (1-4). Treatment of human cells with genotoxic agents induces ATM/ATR-dependent phosphorylation of Rad17 at Ser635 and Ser645. Rad17 phosphorylation is a critical early event during checkpoint signaling in DNA-damaged cells (5-7).
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 77 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen A recombinant protein of human RAD17
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym CCYC, R24L, RAD24, HRAD17, RAD17SP
This product is for research use only, not for diagnostic or therapeutic use!

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