BAIAP2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP10458-01 50ul 1500.00 In Stock
ARP10458-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 10458
Isotype: IgG Swiss Prot: Q9UQB8
purity: Affinity purification
Background:
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 61kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
Immunogen A recombinant protein of human BAIAP2
Storage Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym BAP2, FLAF3, IRSP53
This product is for research use only, not for diagnostic or therapeutic use!

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