Source: | Rabbit | Gene Id: | 25780 |
Isotype: | IgG | Swiss Prot: | Q8IV61 |
purity: | Affinity purification |
Background: |
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 78 kDa |
Recommended Dilutions |
WB 1:200-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human RASGRP3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GRP3 |
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