| No | Size | Price | Availability | |
| ARP23533-01 | 50ul | 1500.00 | In Stock |  |
| ARP23533-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 23533 |
| Isotype: | IgG | Swiss Prot: | Q8WYR1 |
| purity: | Affinity purification |
| Background: |
| Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 97 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IF 1:50-1:100
|
| Immunogen | A recombinant protein of human PIK3R5 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | p101, FOAP-2, P101-PI3K, F730038I15Rik |
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