| No | Size | Price | Availability | |
| ARP11609-01 | 50ul | 1500.00 | In Stock |  |
| ARP11609-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 11609 |
| Isotype: | IgG | Swiss Prot: | Q8WZA2 |
| purity: | Affinity purification |
| Background: |
| Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family. The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane. Erlin-1 may be involved in dentritic cell activation and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 116 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human RAPGEF4 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EPAC, CGEF2, EPAC2, EPAC 2, Nbla00496, CAMP-GEFII |
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