| No | Size | Price | Availability | |
| ARP7296-01 | 50ul | 1500.00 | In Stock |  |
| ARP7296-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7296 |
| Isotype: | IgG | Swiss Prot: | Q16881 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IP IF FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 55 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:100
FC 1:20-1:50
|
| Immunogen | A recombinant protein of human TXNRD1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | TR, TR1, TXNR, TRXR1, GRIM-12 |
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