MNDA Rabbit Polyclonal Antibody
No Size Price Availability  
ARP4332-01 50ul 1500.00 In Stock
ARP4332-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4332
Isotype: IgG Swiss Prot: P41218
purity: Affinity purification
Background:
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 46 kDa
Recommended Dilutions
WB 1:1000-1:2000
Immunogen A recombinant protein of human MNDA
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym PYHIN3
This product is for research use only, not for diagnostic or therapeutic use!

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