| No | Size | Price | Availability | |
| ARP3833-01 | 50ul | 1500.00 | In Stock |  |
| ARP3833-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3833 |
| Isotype: | IgG | Swiss Prot: | Q9BW19 |
| purity: | Affinity purification |
| Background: |
| Kinesin superfamily proteins (KIFs) are molecular motors that drive directional, microtubule-dependent intracellular transport of membrane-bound organelles and other macromolecules (e.g. proteins, nucleic acids). The intracellular transport functions of KIFs are fundamentally important for a variety of cellular functions, including mitotic and meiotic division, motility/migration, hormone and neurotransmitter release, and differentiation (1-4). Disruptions to KIF-mediated intracellular transport have been linked with a variety of pathologies, ranging from tumorigenesis to defects in higher order brain function such as learning and memory (4-6).KIFC1/HSET is a minus-end directed KIF involved in the processing and movement of early endocytic vesicles (7,8), as well as microtubule crosslinking and spindle assembly (9,10). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 74 kDa |
| Recommended Dilutions |
WB 1:200-1:2000
IHC 1:50-1:200
IF 1:50-1:100
|
| Immunogen | A recombinant protein of human KIFC1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | HSET, KNSL2 |
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