
| Source: | Rabbit | Gene Id: | 4791 |
| Isotype: | IgG | Swiss Prot: | Q00653 |
| purity: | Affinity purification |
| Background: |
| This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 97 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide of human NFKB2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | p52, p105, H2TF1, LYT10, LYT-10, NF-kB2 |
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