RUNX2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP860-01 50ul 1500.00 In Stock
ARP860-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 860
Isotype: IgG Swiss Prot: Q13950
purity: Affinity purification
Background:
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 57 kDa
Recommended Dilutions
WB 1:200-1:1000
IHC 1:20-1:50
Immunogen A synthetic peptide of human RUNX2
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym CCD, AML3, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1
This product is for research use only, not for diagnostic or therapeutic use!

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