| No | Size | Price | Availability | |
| ARP8649-01 | 50ul | 1500.00 | In Stock |  |
| ARP8649-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8649 |
| Isotype: | IgG | Swiss Prot: | Q9UHA4 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 14 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
| Immunogen | A fusion protein of human MAPKSP1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MP1, MAPBP, MAPKSP1, PRO0633, MAP2K1IP1, Ragulator3, LAMTOR3 |
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