AIFM1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP9131-01 50ul 1500.00 In Stock
ARP9131-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 9131
Isotype: IgG Swiss Prot: O95831
purity: Affinity purification
Background:
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 66 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
Immunogen A recombinant protein of human AIFM1
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym AIF, CMTX4, COWCK, PDCD8, COXPD6
This product is for research use only, not for diagnostic or therapeutic use!

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