MRE11A Rabbit Polyclonal Antibody
No Size Price Availability  
ARP4361-01 50ul 1500.00 In Stock
ARP4361-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4361
Isotype: IgG Swiss Prot: P49959
purity: Affinity purification
Background:
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 80 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen A recombinant protein of human MRE11A
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ATLD, HNGS1, MRE11, MRE11B
This product is for research use only, not for diagnostic or therapeutic use!

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