BIK Rabbit Polyclonal Antibody
No Size Price Availability  
ARP638-01 50ul 1500.00 In Stock
ARP638-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 638
Isotype: IgG Swiss Prot: Q13323
purity: Affinity purification
Background:
Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2 (1,2). Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins (3). Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity (4).
Reactivity Human
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 18 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen A recombinant protein of human BIK
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym BP4, NBK, BIP1
This product is for research use only, not for diagnostic or therapeutic use!

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