UHRF1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP29128-01 50ul 1500.00 In Stock
ARP29128-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 29128
Isotype: IgG Swiss Prot: Q96T88
purity: Affinity purification
Background:
UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.
Reactivity Human,
Tested applications WB IHC IF IP CHIP
Clonality Polyclonal Antibody
Calculated MW 91kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20- 1:50
ChIP 1:20- 1:50
Immunogen A recombinant protein of human UHRF1
Storage Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95
This product is for research use only, not for diagnostic or therapeutic use!

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