Source: | Rabbit | Gene Id: | 5378 |
Isotype: | IgG | Swiss Prot: | P54277 |
purity: | Affinity purification |
Background: |
PMS1 belongs to the DNA mismatch repair mutL/hexB family. It is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other proteins involved in the HNPCC phenotype, which is also known as Lynch syndrome (1). 1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8. |
Reactivity | Human, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 106kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
Immunogen | A recombinant protein of human PMS1 |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | DKFZp781M0253, FLJ98259, HNPCC3, PMSL1, hPMS1, PMS1 |
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