
| Source: | Rabbit | Gene Id: | 10395 |
| Isotype: | IgG | Swiss Prot: | Q96QB1 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene. |
| Reactivity | Human, Mouse, |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 171kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human DLC1 |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | HP, ARHGAP7, STARD12, p122-RhoGAP |
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