POLH Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5429-01 50ul 1500.00 In Stock
ARP5429-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5429
Isotype: IgG Swiss Prot: Q9Y253
purity: Affinity purification
Background:
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq, Jul 2008]
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 78kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunogen A recombinant protein of human POLH
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym FLJ16395, FLJ21978, RAD30, RAD30A, XP-V, XPV
This product is for research use only, not for diagnostic or therapeutic use!

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