| No | Size | Price | Availability | |
| ARP5771-01 | 50ul | 1500.00 | In Stock |  |
| ARP5771-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5771 |
| Isotype: | IgG | Swiss Prot: | P17706 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 49kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
|
| Immunogen | A recombinant protein of human PTPN2 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | PTN2, PTPT, TCPTP, TC-PTP, TCELLPTP |
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