Source: | Rabbit | Gene Id: | 4973 |
Isotype: | IgG | Swiss Prot: | P78380 |
purity: | Affinity purification |
Background: |
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. |
Reactivity | Human, |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 31kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
Immunogen | A recombinant protein of human OLR1 |
Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | LOX1, LOXIN, SLOX1, CLEC8A, SCARE1 |
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