
| Source: | Rabbit | Gene Id: | 3456 | 
| Isotype: | IgG | Swiss Prot: | P01574 | 
| purity: | Affinity purification | 
| Background: | 
| The genes encoding type I interferons (IFNs), which include 14 IFN-? genes, one IFN-∫ gene, one IFN-w (also known as IFN-? II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-? and -∫ are cytokines that are widely known to induce potent antiviral activity. IFN-? and -∫ exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-?, IFN-∫ or IFN-?, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-?R) interacts with IFN-?, IFN-∫ and IFN-w, and seems to be a multisubunit receptor. | 
| Reactivity | Human, | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 22kDa | 
| Recommended Dilutions | 
                                     WB 1:500 - 1:2000 
                                    IHC 1:50 - 1:200 
                                    IF 1:50- 1:200 
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | A recombinant protein of human IFNB1 | 
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | IFNB1,IFB,IFF, IFNB,MGC96956 | 
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