Source: | Rabbit | Gene Id: | 9429 |
Isotype: | IgG | Swiss Prot: | Q9UNQ0 |
purity: | Affinity purification |
Background: |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon. |
Reactivity | Human, Mouse |
Tested applications | WB IHC ICC FC |
Clonality | Polyclonal Antibody |
Calculated MW | 72 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:500
ICC 1:200-1:500
FC 1:50- 1:200
|
Immunogen | A recombinant protein of human ABCG2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, CDw338, EST157481, MGC102821 |
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