
| Source: | Rabbit | Gene Id: | 6382 | 
| Isotype: | IgG | Swiss Prot: | P18827 | 
| purity: | Affinity purification | 
| Background: | 
| The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] | 
| Reactivity | Human | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 33kDa | 
| Recommended Dilutions | 
                                     WB 1:500 - 1:2000 
                                    IHC 1:50 - 1:200 
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A recombinant protein of human SDC1 | 
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | SDC1,CD138,SDC,SYND1,syndecan | 
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