| No | Size | Price | Availability | |
| ARP3575-01 | 50ul | 1500.00 | In Stock |  |
| ARP3575-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3575 |
| Isotype: | IgG | Swiss Prot: | P16871 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 52kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
|
| Immunogen | A recombinant protein of human IL7R |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | IL7R,CD127,CDW127,IL-7R-alpha,IL7RA,ILRA |
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