Source: | Rabbit | Gene Id: | 942 |
Isotype: | IgG | Swiss Prot: | P42081 |
purity: | Affinity purification |
Background: |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
Reactivity | Human, Mouse |
Tested applications | WB IHC ICC IF IP |
Clonality | Polyclonal Antibody |
Calculated MW | 38kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:100
ICC 1:50- 1:100
|
Immunogen | A recombinant protein of human CD86 |
Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CD86,B7-2,B70,CD28LG2,LAB72,MGC34413 |
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