Source: | Rabbit | Gene Id: | 81788 |
Isotype: | IgG | Swiss Prot: | Q9H093 |
purity: | Affinity purification |
Background: |
SNARK was identified as an SNF1/AMPK-related kinase and member of the AMPK catalytic subunit family (1,2). This enzyme was separately identified as a TNFα-induced SNF1-like kinase 2 (NUAK2) (3). The kinase activity of SNARK/NUAK2 is increased by AMP and AICAR (1). SNARK/NUAK2 activity is regulated by a variety of cellular stresses such as endoplasmic reticulum (ER) stress and oxidative stresses (4), suggesting that SNARK/NUAK2 is a signaling molecule involved in the cell stress response (4). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 70 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human NUAK2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | NUAK2, DKFZp434J037, DKFZp686F01113, FLJ90349, SNARK |
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