| No | Size | Price | Availability | |
| ARP811-01 | 50ul | 1500.00 | In Stock |  |
| ARP811-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 811 |
| Isotype: | IgG | Swiss Prot: | P27797 |
| purity: | Affinity purification |
| Background: |
| Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding and apoptosis. Calcium is stored in the endoplasmic reticulum (ER), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor (1). Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such, calreticulin presumably does not alter protein folding but ensures proper timing for efficient folding and subunit assembly. Furthermore, calreticulin retains proteins in non-native conformation within the ER and targets them for degradation (2,3). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IP IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:20-1:100
ICC 1:20-1:100
|
| Immunogen | A recombinant protein of human CALR |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CALR, CRT, FLJ26680, RO, SSA, cC1qR |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
