| No | Size | Price | Availability | |
| ARP7172-01 | 50ul | 1500.00 | In Stock |  |
| ARP7172-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7172 |
| Isotype: | IgG | Swiss Prot: | P51580 |
| purity: | Affinity purification |
| Background: |
| This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 28kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human TPMT |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | TPMT, Thiopurine methyltransferase, thiopurine S methyltransferase |
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