| No | Size | Price | Availability | |
| ARP2180-01 | 50ul | 1500.00 | In Stock |  |
| ARP2180-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2180 |
| Isotype: | IgG | Swiss Prot: | P33121 |
| purity: | Affinity purification |
| Background: |
| ACSL1(Long-chain-fatty-acid--CoA ligase 1) is also named as FACL1, FACL2, LACS, LACS1, LACS2 and belongs to the ATP-dependent AMP-binding enzyme family. ACSL1 is a 75 kDa protein that is associated peripherally with the plasma membrane(Brian M Wiczer, etc., 2006). ACSL1 is abundantly expressed in tissues, such as liver and brown fat, that metabolize substantial amounts of triglycerides as fuel, and as such, a deficiency in ACSL1 function could have a more profound affect in those cells, resulting in hepatosteatosis and potentially increased very low density lipoprotein production by the liver or decreased thermogenic capacity in brown adipose tissue(PMID:19429676). An anti-rat ACSL1 antibody recognized a band of the predicted 68 kDa in high-speed supernatant from rat liver and in human and murine SMCs, monocyte-derived macrophages, and murine peritoneal macrophages(PMID:17259370). It has 2 isoforms produced by alternative splicing. This antibody is specific to ACSL1. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 78 kDa |
| Recommended Dilutions |
WB 1:200-1:1000
|
| Immunogen | A recombinant protein of human ACSL1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ACS1, FACL1, FACL2, LACS, LACS1, LACS2 |
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