| No | Size | Price | Availability | |
| ARP2956-01 | 50ul | 1500.00 | In Stock |  |
| ARP2956-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2956 |
| Isotype: | IgG | Swiss Prot: | P52701 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 153 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:20-1:100
|
| Immunogen | A recombinant protein of human MSH6 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MSH6, GTBP, HNPCC5, HSAP |
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