PRKCZ Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5590-01 50ul 1500.00 In Stock
ARP5590-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5590
Isotype: IgG Swiss Prot: Q05513
purity: Affinity purification
Background:
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reactivity Human, Mouse
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 68 kDa
Recommended Dilutions
WB 1:500-1:1000
IHC 1:50-1:100
Immunogen A synthetic peptide of human PRKCZ
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym PKC2, PKC-ZETA
This product is for research use only, not for diagnostic or therapeutic use!

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