| No | Size | Price | Availability | |
| ARP3655-01 | 50ul | 1500.00 | In Stock |  |
| ARP3655-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3655 |
| Isotype: | IgG | Swiss Prot: | P23229 |
| purity: | Affinity purification |
| Background: |
| Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1,2).Integrin α6 is a 120 kDa protein with two splice variants, integrin α6, 6A and 6B (3), which function as receptors for laminins on the basal membrane to mediate cellular adhesion events (4-6). α6 integrins have been shown to play an important role in hematopoietic stem and progenitor cell homing to the bone marrow. |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 127 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
IF 1:20-1:50
|
| Immunogen | A synthetic peptide of human ITGA6 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CD49f, VLA-6, ITGA6B |
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