| No | Size | Price | Availability | |
| ARP27329-01 | 50ul | 1500.00 | In Stock |  |
| ARP27329-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 27329 |
| Isotype: | IgG | Swiss Prot: | Q9Y5C1 |
| purity: | Affinity purification |
| Background: |
| Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?(v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 54kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
|
| Immunogen | A recombinant protein of human ANGPTL3 |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | ANGPTL3,ANGPT5 |
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