| No | Size | Price | Availability | |
| ARP23164-01 | 50ul | 1500.00 | In Stock |  |
| ARP23164-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 23164 |
| Isotype: | IgG | Swiss Prot: | Q6WCQ1 |
| purity: | Affinity purification |
| Background: |
| MPRIP, also named as KIAA0864, MRIP, RHOIP3 and p116Rip, is required for the regulation of the actin cytoskeleton by RhoA and ROCK1. MRPIP targets myosin phosphatase to the actin cytoskeleton. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. The antibody recognizes the C-term of isoform2 and isoform3 of MPRIP. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 117 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
IF 1:20-1:50
|
| Immunogen | A fusion protein of human MPRIP |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MPRIP, KIAA0864, M-RIP, RHOIP3, p116Rip |
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