| No | Size | Price | Availability | |
| ARP2887-01 | 50ul | 1500.00 | In Stock |  |
| ARP2887-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2887 |
| Isotype: | IgG | Swiss Prot: | Q13322 |
| purity: | Affinity purification |
| Background: |
| Growth factor receptor-bound protein 10 (GRB10) is an adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. GRB10 has three consensus domains including pleckstrin homology (PH) domain, SH2/SH3 domain and Ras-associating domain. By binding to kinases, GRB10 suppresses signals from activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. It may play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 61 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A recombinant protein of human GRB10 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GRB-IR, Grb-10, IRBP, KIAA0207, MEG1, RSS |
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