| No | Size | Price | Availability | |
| ARP2969-01 | 50ul | 1500.00 | In Stock |  |
| ARP2969-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2969 |
| Isotype: | IgG | Swiss Prot: | P78347 |
| purity: | Affinity purification |
| Background: |
| The GTF2I gene encodes a transcription factor. It negatively regulates agonist-induced calcium entry into cells by interfering with expression of the cation channel TRPC3 at the plasma membrane [PMID: 17023658]. As a transcription factor and/or as a regulator of intracellular calcium levels, GTF2I may play a role in the molecular basis of anxiety[PMID: 22578324]. It interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation [PMID: 16738337]. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 112 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IF 1:20-1:50
|
| Immunogen | A recombinant protein of human GTF2I |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BAP-135, BAP135, BTKAP1, DIWS, FLJ38776, FLJ56355, IB291, SPIN, TFII-I, WBS, WBSCR6 |
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