| No | Size | Price | Availability | |
| ARP2081-01 | 50ul | 1500.00 | In Stock |  |
| ARP2081-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2081 |
| Isotype: | IgG | Swiss Prot: | O75460 |
| purity: | Affinity purification |
| Background: |
| Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 109 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide of human ERN1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, Serine/threonine-protein kinase, Endoribonuclease |
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