Source: | Rabbit | Gene Id: | 9414 |
Isotype: | IgG | Swiss Prot: | Q9UDY2 |
purity: | Affinity purification |
Background: |
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 134 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A recombinant protein of human TJP2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MGC26306, X104, ZO-2, ZO2 |
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