| No | Size | Price | Availability | |
| ARP12364-01 | 50ul | 1500.00 | In Stock |  |
| ARP12364-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 12364 |
| Isotype: | IgG | Swiss Prot: | Q6UXS9 |
| purity: | Affinity purification |
| Background: |
| Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels. Caspase-12 Antibody detects endogenous levels of full-length caspase-12 protein (50 kDa) and its cleaved product (40-44 kDa). This antibody does not cross-react with other caspases. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 39 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:20-1:200
IF 1:10-1:100
|
| Immunogen | A synthetic peptide of human CASP12 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CASP12P1 |
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