Source: | Rabbit | Gene Id: | 3984 |
Isotype: | IgG | Swiss Prot: | P53667 |
purity: | Affinity purification |
Background: |
LIMK1,also named LIMK, belongs to the protein kinase superfamily and TKL Ser/Thr protein kinase family. LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. LIMK1 may be involved in brain development. The antibody has no cross-reaction with LIMK2. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 73 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide of human LIMK1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | LIMK |
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