NUP98 Rabbit Polyclonal Antibody
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ARP4928-01 50ul 1500.00 In Stock
ARP4928-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4928
Isotype: IgG Swiss Prot: P52948
purity: Affinity purification
Background:
Nup98-Nup96 (also known as Nup196, ADIR2 or ADAR2), encoded by NUP98 gene, is a component of the nuclear pore complex (NPC) . It is first synthesized as 186-198 kDa Nup98-Nup96 precursors and the precursors shortly undergo autoproteolysis to give rise to two nucleoporins, the amino-terminal Nup98 (Nup98-N) and carboxy-terminal Nup96 (Nup96-C). Both of Nup98 and Nup96 are localized to the nucleoplasmic side of the NPC. This antibody was raised against the carboxy-terminal region of Nup98-Nup96, it recognizes all Nup98-Nup96 proteins except Nup98-N. Since the autoproteolysis is very rapid this antibody usually detected 98-115 kDa Nup96 protein in multiple cell lines. It is notable that RNA-editing deaminase 1 (Gene ID: 104), also named ADAR2, is a different protein from Nup98-Nup96 (ADAR2).
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 98 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A recombinant protein of human NUP98
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ADIR2, NUP196, NUP96
This product is for research use only, not for diagnostic or therapeutic use!

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