Source: | Rabbit | Gene Id: | 4613 |
Isotype: | IgG | Swiss Prot: | P04198 |
purity: | Affinity purification |
Background: |
MYCN, also named as BHLHE37 and NMYC, is a transcription factor. It is primarily expressed in normal developing embryos and is thought to be critical in brain and other neural development. It is often amplified in human neuroblastomas. IR34A can suppress MYCN expression, it suggest MYCN has a role in cell growth. The expression of the MCYN is upregulated in a variety of human tumors, most requently neuroblastoma, where the level of expression appearts to increase as teh tumor progress. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 65 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A recombinant protein of human MYCN |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | NMYC, ODED, MODED, N-myc, MYCNOT, bHLHe37 |
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