| No | Size | Price | Availability | |
| ARP22900-01 | 50ul | 1500.00 | In Stock |  |
| ARP22900-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 22900 |
| Isotype: | IgG | Swiss Prot: | Q9Y2G2 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 49kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human CARD8 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | CARD8,CARDINAL,DACAR,DKFZp779L0366,Dakar,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP,NDPP1,TUCAN |
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