TYMS Rabbit Polyclonal Antibody
No Size Price Availability  
ARP7298-01 50ul 1500.00 In Stock
ARP7298-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7298
Isotype: IgG Swiss Prot: P04818
purity: Affinity purification
Background:
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 36 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:20-1:50
Immunogen A recombinant Protein of human TYMS
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym HsT422, MGC88736, TMS, TS, TSase
This product is for research use only, not for diagnostic or therapeutic use!

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