
| Source: | Rabbit | Gene Id: | |
| Isotype: | IgG | Swiss Prot: | P06800 |
| purity: | Purified by Protein A. |
| Background: |
| Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity. |
| Reactivity | Mouse |
| Tested applications | FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
FC 1:20-1:100
|
| Immunogen | KLH conjugated synthetic peptide derived from mouse CD45 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Lymphocyte antigen 5, L-CA, Ly-5, T200 |
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