STAT2 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP20181-01 50ul 1500.00 In Stock
YRP20181-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 6773
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Reactivity Human
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human STAT2
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym Signal transducer and activator of transcription 2
This product is for research use only, not for diagnostic or therapeutic use!

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