Source: | Rabbit | Gene Id: | 7097 |
Isotype: | IgG | Swiss Prot: | O60603 |
purity: | Purified by Protein A. |
Background: |
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
|
Immunogen | KLH conjugated synthetic peptide derived from human TLR2 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | TIL4, CD282, Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, TLR2 |
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