ARM6772P-21C [Monoclonal Antibody]
Phospho-STAT1-Tyr701 Rabbit Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
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Species:   Rabbit
Applications:   FC
Immunogen Range:   A synthetic phosphopeptide corresponding to residues surrounding Tyr701 of human Stat1
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   6772
Swiss Prot:   P42224
Synonyms:   CANDF7, ISGF-3, STAT91
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Caculated MW:   84, 91 kDa
Observed MW:   Refer to Figures
Applications:   FC 1:50
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information