ARP79188-01
[Polyclonal Antibody]
TMEM43 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
Recombinant protein of human TMEM43 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
79188 |
Swiss Prot: |
Q9BTV4 |
Synonyms: |
LUMA, ARVC5, ARVD5, EDMD7 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. |
Caculated MW: |
45kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!